Is this suitable for very sensitive skin?

NeuroCalm Serum

Price

When skin is stressed, nothing else works properly. NeuroCalm brings it back to balance - at the source.

Size

30ml · ~120 applications

Mini · 5ml

Estimated delivery: Calculating…

✓ Free shipping €50+ (DE)

✓ Dermatologically tested (Dermatest – “Sehr gut”)

✓ Sensitive-skin first — designed to support barrier resilience.

✓ Earn Glow Points. Join The Insider Club

Calm · Reactivity Control · Stress Resilience

Best for: Stress-triggered reactivity, redness and flushing, over-treated or barrier-compromised skin, rosacea-prone skin or highly reactive skin - especially when 'nothing seems to work' anymore.

Not ideal for: Those seeking pigmentation correction, glow enhancement, visible firming, or wrinkle-focused results.

Routine step: Treat (Step 3 of 5) - Use after PREP and before your moisturiser. In highly reactive phases, it can be used as the only treatment step.

Choose if your priority is: If your skin flushes, stings, suffer from allergies, histamin intolerance.

*If your skin is easily triggered or prone to redness, explore our Redness & Sensitive Skin routines for a barrier-first approach.

What Makes It Special

✔ Powered by NeuroSooth Complex™ - a proprietary blend that targets the skin–stress axis to visibly reduce reactivity and redness.

✔ Neuro-regulatory precision - addresses stress-driven signalling pathways linked to flushing, tightness, and barrier fatigue.

✔ Barrier-first resilience - reinforces hydration and structural stability so skin can recover and adapt over time.

✔ Advanced bioactive architecture - combines ectoin, PAD, sphingolipids and targeted peptides in intelligent concentrations without overload.

✔ Makes every routine work better - restores stable skin behaviour so other treatments can perform at their full potential.

Skin Action & What to Expect

Stress Signalling · Barrier Stability · Skin Equilibrium

NeuroCalm is not a comfort serum. It is a neuro-regulatory treatment that addresses stress-driven signalling pathways responsible for redness, tightness and hypersensitivity.

Rather than suppressing symptoms, NeuroCalm helps reactive skin return to stable function — reinforcing resilience, improving tolerance and restoring structural balance over time.

Skin Action

Modulate Stress Signalling

NeuroCalm targets pathways involved in the skin’s stress response, helping reduce visible signs of stress-driven reactivity such as redness, tightness and flushing. Skin appears calmer, less reactive and more evenly toned.

Interrupt the Inflammatory Cycle

Daily emotional and environmental stress can leave skin in a constant low-grade inflammatory state. By supporting regulatory pathways and barrier lipids, NeuroCalm helps break this cycle. Over time, skin appears less easily triggered and more behaviourally stable.

Rebuild Tolerance Without Overload

Instead of relying on aggressive actives, the formula reinforces hydration architecture and barrier integrity so sensitised skin can recover naturally. Skin feels more comfortable and better able to tolerate both environmental exposure and active skincare routines.

Restore Visible Stability

With consistent use, redness appears more controlled, texture looks smoother and the complexion appears more balanced — supporting both physical comfort and a visibly calmer appearance.

Formulated to support the skin’s regulatory systems rather than override them.

---------------------------------------------------------------

Proven Results – What to Expect

NeuroCalm reduces the visible impact of stress-driven reactivity. Results build progressively with consistent use.

From first application

Skin feels calmer and more comfortable. Tightness and irritation appear reduced, and hydration balance improves.

After 2–4 weeks

Redness appears more controlled. Skin looks more even and less easily triggered, with improved tolerance to daily skincare.

After 6–12 weeks

Barrier resilience strengthens. Reactivity appears reduced and overall skin stability improves.

Developed for long-term regulation and tolerance — not short-term suppression.

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NeuroCalm Serum

Redness looks less intense

Flushing and stress-related redness appear more controlled.

That “hot” feeling softens

Tightness, sting-proneness and reactive discomfort feel reduced.

Skin behaves more predictably

Less overreaction to stress, weather, or active ingredients.

SKIN SCIENCE

CLINICAL RESULTS

Results based on a consumer perception study.

94%

said their skin felt less reactive and more comfortable*

91%

reported redness and flushing looked more controlled*

88%

said their skin tolerated daily skincare better (less stinging/tightness)*

after 28 days

Visible reduction in stress-related redness**

*Results build cumulatively. NeuroCalm is designed for long-term structural support, not short-term plumping. **Instrumental measurement on the active ingredient / supplier testing.

The Ritual

How to use

☼ Apply 1–2 pumps to clean, dry skin every morning and/or evening. Massage gently until absorbed. Follow with your moisturiser.

💡 Sarah’s Tip: “Use consistently for at least 21 days - especially during periods of stress, seasonal change, hay fever, or skin flare-ups. NeuroCalm works best when used daily to help skin re-establish calm, tolerance, and balance.”

WHAT IT IS

Neuro-Regulatory Stress Control for Reactive Skin

NeuroCalm Serum is a high-performance neuro-regulatory treatment that addresses the skin–stress axis - the signalling pathways that drive redness, tightness, and hypersensitivity when skin becomes overwhelmed.

Rather than masking symptoms, NeuroCalm helps normalise how skin behaves under stress. Powered by our proprietary NeuroSooth™ Complex, it combines clinically studied bioactives to reinforce stress resilience, strengthen barrier stability, and rebuild tolerance over time.

This lightweight, silky formula pairs targeted redness-modulating peptides with oat-derived avenanthramides, ectoin, and barrier-supportive hydration architecture to visibly reduce reactivity while restoring equilibrium to sensitised skin.

With consistent use, skin appears calmer, more even, and less easily triggered - not simply soothed, but functioning normally again.

Dermatologically tested. Fragrance-free. Vegan.

WHAT IS INSIDE?

Every active is selected for performance and skin tolerance - never for trend or sensory effect.

Supporting Environmental Recovery

Daily exposure to UV and environmental stress contributes to cumulative sensitivity.

Micrococcus Lysate

Studied in cellular models for its role in supporting recovery from environmental stress exposure.

This helps maintain skin equilibrium in the face of daily triggers.

Modulating Stress Reactivity

Reactive skin is often driven by amplified inflammatory and neuro-sensory signalling.

Avenanthramides

Studied in the literature for their anti-inflammatory and anti-irritant activity, including support of pathways involved in neurogenic inflammation.

Acetyl Hexapeptide-49

A targeted neuro-soothing peptide studied for its role in reducing visible signs of sensory irritation and stress-related reactivity.

Acetyl Tetrapeptide-40

A peptide complex commonly studied for visible redness modulation and sensitivity-prone skin.

Together, these actives help reduce visible stress reactivity and support a calmer skin response to triggers.

Strengthening Barrier Stability

Stress weakens barrier function, increasing TEWL and sensitivity.

Ectoin

A well-documented stress-protection molecule studied in human trials for improving hydration and reducing transepidermal water loss (TEWL), helping reinforce barrier resilience.

Potassium Azeloyl Diglycinate (PAD)

A water-soluble azelaic derivative studied for visible redness control and improved tone clarity in sensitive skin.

NMF + Sphingolipid Complex

Supports hydration pathways essential for barrier integrity and tolerance.

This multi-pathway approach helps reduce visible stress fatigue while improving overall barrier stability.

Supporting Environmental Recovery
Daily exposure to UV and environmental stress contributes to cumulative sensitivity.
Micrococcus Lysate
Studied in cellular models for its role in supporting recovery from environmental stress exposure.
This helps maintain skin equilibrium in the face of daily triggers.
Modulating Stress Reactivity
Reactive skin is often driven by amplified inflammatory and neuro-sensory signalling.
Avenanthramides
Studied in the literature for their anti-inflammatory and anti-irritant activity, including support of pathways involved in neurogenic inflammation.
Acetyl Hexapeptide-49
A targeted neuro-soothing peptide studied for its role in reducing visible signs of sensory irritation and stress-related reactivity.
Acetyl Tetrapeptide-40
A peptide complex commonly studied for visible redness modulation and sensitivity-prone skin.
Together, these actives help reduce visible stress reactivity and support a calmer skin response to triggers.
Strengthening Barrier Stability
Stress weakens barrier function, increasing TEWL and sensitivity.
Ectoin
A well-documented stress-protection molecule studied in human trials for improving hydration and reducing transepidermal water loss (TEWL), helping reinforce barrier resilience.
Potassium Azeloyl Diglycinate (PAD)
A water-soluble azelaic derivative studied for visible redness control and improved tone clarity in sensitive skin.
NMF + Sphingolipid Complex
Supports hydration pathways essential for barrier integrity and tolerance.
This multi-pathway approach helps reduce visible stress fatigue while improving overall barrier stability.

Immediate

Sensory relief + comfort

Skin feels calmer and less reactive. The formula is designed to reduce the sensation of irritation and stress without suppressing the skin’s natural functions.

2–4 weeks

Reduced reactivity

Visible redness and stress responses appear less intense. Skin feels more balanced and better able to tolerate daily exposure.

6–8 weeks

Strengthened barrier + recovery

Skin looks more even, resilient, and stable. Sensitivity episodes may feel less frequent as the barrier and stress response normalise.

Selected references

[1]
Neuro-inflammation & skin reactivity: Research shows that neuro-mediated inflammation plays a role in sensitive and reactive skin conditions. Read
[2]
Ectoin & cellular stress protection: Studies demonstrate ectoin’s ability to protect cells from environmental and oxidative stress. Read
[3]
Barrier function & inflammatory signalling: Scientific literature indicates that strengthening barrier integrity helps reduce inflammatory responses in compromised skin. Read

2,200+

Substances excluded (Restricted List)

Film-former free

No film-formers, no sensory fillers

EU+

Beyond EU requirements

Explore our standards

Any questions? Let us answer them

All NAYA products are formulated to be gentle and barrier-respecting. This product was dermatologically tested by Dermatest and rated “Sehr gut/excellently” on sensitive skin. If your skin is highly reactive or you’re trying NAYA for the first time, we recommend introducing new products gradually. Minis, the Skin Quiz or a consultation can help you choose comfortably.

NeuroCalm Serum

NeuroCalm Serum

What Makes It Special

Skin Action & What to Expect

Stress Signalling · Barrier Stability · Skin Equilibrium

Skin Action

Modulate Stress Signalling

Interrupt the Inflammatory Cycle

Rebuild Tolerance Without Overload

Restore Visible Stability

Proven Results – What to Expect

Customers also bought

Redness looks less intense

That “hot” feeling softens

Skin behaves more predictably

CLINICAL RESULTS ⓘ

How to use

WHAT IT IS